Design better
molecules. Faster.
Explore new formats. Validate with confidence. Unlock your history.
BioGlyph is the complete platform for designing, validating, and registering therapeutic molecules. Design formats your old tools wouldn't allow, build on validated components from your history, and get to market first.
Trusted by top pharmas
Three strengths, one system.
Format Design, simplified
The Design Pad closes the gap between your toolset and your imagination. Design any format by dragging and dropping Building Blocks.
Assemble a molecule from typed building blocks — drag, connect, export.
Open the Design PadYour old molecules still have answers.
Decipher brings your historical molecules into the system as first-class citizens. Understand what made them work — and use that to design better molecules today.
You've designed hundreds of molecules and tested thousands of variants. You've learned what works and what doesn't — but that knowledge is buried in old project folders and scientists' heads, lost when people leave.
Decipher changes that. From just sequence inputs, it brings your molecules to life — uncovering what drove performance, which components performed best, which formats showed promise, and which properties predicted success. All visible. All queryable. All actionable.
You design informed by decades of your own experimentation. You move faster, make fewer mistakes, and hold an advantage competitors can't replicate — they don't have your data.
One molecule. One complete picture.
Every molecule is a complete digital twin — blocks, chains, codons, structure and bench results, all connected and all queryable. Pull it apart.
Comprehensive molecule design, from format design through expression
From a blank canvas to lab-ready entities — one continuous, traceable workflow. No exports, no reformatting, no handoffs lost between tools.
01
Design format
Generate the format in DesignPad — monoclonals, bispecifics, multispecifics, fusion proteins, ADCs.
02
Assemble components
Stitch validated, reusable building blocks — Fabs, Fc, Fvs, hinges — into the formats you designed.
03
Register entities
Panel Generation creates registered molecular entities, each fully traceable: which components, which format, why.
04
Lab-ready
Registered entities move straight to cloning via Luma or Geneious — lab- and manufacturing-ready.
Best-in-class ADCs
Combine BioGlyph's rich biologics representation with Dotmatics' advanced chemistry software to bring your ADCs to life.
Antibody, linker and payload assembled in one system.
Learn moreEngineer molecules
Leverage sequence, 3D structure, and experimental data to reengineer variable regions, building blocks, and molecules without ever leaving the system.
Sequence, structure and assay data side by side while you edit.
Learn moreStructure informed development
BioGlyph's rich data model provides a foundation for full-length, format-agnostic 3D modeling, providing for next-generation insights in molecule selection, purification development, formulation design, and more.
Format-agnostic 3D models of full-length multispecifics.
Learn moreScreening, expression, purification, and registration.
Cloning Design & Execution
Molecular designs are broken into parts. Scientists use Geneious to design the cellular components for making the parts, which are then made in the lab.
Plasmid Design & Assembly
Each construct becomes an annotated plasmid map. Cloning steps are simulated and documented in SnapGene before anything is built at the bench.
Express, Purify & Structural Characterization
The cellular components from the prior step are inserted into living cells that make the proteins. These must be purified and analyzed for structural detail.
Integrated registration
Functional Assay Development & Execution
Pure proteins are tested for functional properties. These results, intersected with molecular structure, are used for subsequent decisions.
Visual Decision Support at a Glance
Create intuitive decision support dashboards that display all relevant data in a clear, visual format to easily interpret and analyze complex information.
Accelerate with a streamlined workflow
Register hundreds of molecules with diverse formats in minutes, not hours.
De-risk through validation
Validate a component once, then reuse it with confidence across programs and formats.
Full traceability
Every registered entity traces back to its components and format — complete accountability from design to manufacturing.
One seamless pipeline
Design → panel generation → registration → Luma / Geneious. One platform, no tool fragmentation, works with any LIMS.
Proteins are becoming as composable as software.
Once a molecule is a language, it can be searched, diffed, recombined, and reasoned about by machines. BioGlyph is the notation that gets biology there.
Scientists and engineers who’ve lived the problem — now building the platform they wished they had.
Scientific advisory board
Biologics designs are the most valuable thing you own. BioGlyph is built so they never leave your control.
Your molecules are yours. They are never used to train shared or third-party models.
Industry-standard encryption everywhere your sequences live.
Granular permissions so the right people see the right designs.
Every change versioned, attributed, and reversible.
Dedicated deployments, including on-prem, for enterprise.
Bring us your hardest format.
Request a personalized demo and see how BioGlyph accelerates your discovery. It takes 20 minutes — we'll show you how to design new formats, leverage your history, and register molecules with confidence. No commitment. Just a conversation.